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Synthesis and biological evaluation of some imidazoline derivatives

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Published under licence by IOP Publishing Ltd
, , Citation Hanaa A. Altameemi et al 2020 IOP Conf. Ser.: Mater. Sci. Eng. 871 012030 DOI 10.1088/1757-899X/871/1/012030

1757-899X/871/1/012030

Abstract

The group of imidazoline derivatives is an important class of compounds that possess broad biological activity. Many derivatives that have been efficiently synthesized form 4,5-dihydro-1H-imidazole s starting material to Synthesis of some new Schiff bases, 2-azetidinone and 4-thiazolidinone derivatives .The structures were characterized by FTIR and 1H-NMR spectra. All The synthesized compounds were evaluated for their antimicrobial activities against two kind of bacteria (gram +ve ) [ S .aureus, S.epidermi dis ] and (gram −ve ) [E.co li, Klebsiel lla spp] as well as fungi[C.albica ns] using the micro dilution procedure and compared with amoxicillin activity.

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10.1088/1757-899X/871/1/012030