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Reducing of Defects in the Drug Tablets Production Process with DMAIC to Improve Quality – Study Case of Pharmaceutical Industry

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Published under licence by IOP Publishing Ltd
, , Citation Adha Winatie et al 2020 IOP Conf. Ser.: Mater. Sci. Eng. 852 012126 DOI 10.1088/1757-899X/852/1/012126

1757-899X/852/1/012126

Abstract

The high defect and unstable of defects the company in 2017 amounted to 0.27% while the amount allowed by this company was 0.10%. In This research was carried out in a Pharmaceutical Industry with the purpose of reducing the product spots drug tablets, the research method uses the DMAIC stages Define, Measure, Analyze, Improve and Control. The tools used are SIPOC diagrams, pareto diagrams, P charts, minitabs to calculate sigma levels and improvment with FMEA. The number of reject spots for tablets in 2018 was 0.28% and the sigma level was 4.63, then after analysis and DMAIC the reject rate was reduced to 0.0081% and sigma level 5.45.

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10.1088/1757-899X/852/1/012126