Correlation of Eosinofil and Basophil count with intensity of soil transmitted helminth infection among farmers in Bali

In STH infection, the most important innate immune response on resistance to worm infections are eosinophils and basophils. The purpose of this research is to examine the correlation of eosinophils and basophils with intensity of STH infection among farmers in Bali. In this cross-sectional analytic study, 162 fecal samples from farmers aged 25-80 years were examined by Kato-Kats thick smear method and determined infection intensity based on number of eggs per gram of feces (EPG). Twenty blood samples from STH infected farmer and 20 blood samples from uninfected farmers were examined by flowcytometry method to obtain eosinophils and basophils. The results showed that prevalence of A. lumbricoides single infection was 1.85%, 9,3% of T. trichiura, 0,61% of Hookworm, mixed infection between A. lumbricoides and T. trichiura were 1.2%, mixed infection of A. lumbricoides and Hookworm were 0.61%. There was significant difference of eosinophils and basophils between STH-infected group and uninfected group (p> 0.05). Significant correlation was found between eosinophil count and EPG (r_s = 0,572, p = 0,00), also between basophil count and EPG (r_s = 0.50, p = 0.001). Eosinophils and basophils are significantly correlated with intensity of STH infection among farmer in Bali.