Abstract
Left ventricle (LV) remodeling often occurs after acute myocardial infarction (AMI), and early detection and prompt treatment on this condition may improve prognosis of the patients. Basal soluble ST2 and Global Longitudinal Strain (GLS) 2D-speckle tracking echocardiography can detect early changes before LV remodeling occurs. This is an analytic observational study using one group pre-test and post-test design for correlation. Forty-five patients of AMI during August until December 2015 from ICCU and cardiology ward were analyzed and followed up for 12 weeks. There were 45 subjects with AMI, 38 (84.4%) patients with STEMI and seven (15.6%) patients with NSTEMI. There were significant differences of left ventricle end diastolic volume (LVEDV) baseline from 76±29.69ml/m2 to 98.11±36.84ml/m2 after 12 week follow-up (p=0,003). There was significant correlation between high baseline soluble ST2 with and low GLS baseline with LV remodeling (p=0.015). High baseline soluble ST2 and low GLS value can predict LV remodeling in patients with AMI.
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