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Correlation between Osteoprotegerin Serum Levels and Arterial Stiffness Assessed by Cardio-ankle Vascular Index (CAVI) in Hypertensive Patients

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Published under licence by IOP Publishing Ltd
, , Citation A Ariendanie et al 2020 IOP Conf. Ser.: Earth Environ. Sci. 441 012158 DOI 10.1088/1755-1315/441/1/012158

1755-1315/441/1/012158

Abstract

The cardio-ankle vascular index (CAVI) is a newly developed clinical measurement for evaluating arterial stiffness from the origin of the aorta to the ankle. Osteoprotegerin (OPG) is widely known as a vascular calcification mediator, which have a role to affect atherogenesis. Thirty subjects participated in this research and each subject underwent a CAVI examination to assess arterial stiffness and their blood samples were collected for OPG measurement. This study is analyzed with Pearson Correlation Test. There is a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients. (r = 0.730 and p <0,0001). There was a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients.

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10.1088/1755-1315/441/1/012158