Abstract
There are several factors that affect the efficiency of phagocytic activity in diabetic patients. In this study, a significant difference of phagocytosis efficiency showed in diabetic patients and controls (non-diabetic). The means of phagocytic activity were 43.05%, 52.70% and 71.35% for diabetic foot ulcer, diabetes mellitus patients and controls respectively. Age groups, mean blood glucose levels and controlling fasting blood glucose were significant factors effects on phagocytic activity (P-value = 0.022, 0.013 and 0.045) respectively. There was reverse significant correlation between the mean blood glucose and phagocytic activity (P-value = 0.049; r =-0.314). Wagner grade ulcers classified I and II were the most prevalent 30% for both in diabetic foot ulcer patients. And we found that there is a weak negative correlation between the phagocytic activity efficiency and the grades of the classified ulcers (r =-0.323). In this study, we revealed that the efficiency of phagocytic activity was affected by many factors. Level of blood glucose control was the most important factor.
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