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Design, Synthesis and Biological Screening of New Benzimidazole Derivatives

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Published under licence by IOP Publishing Ltd
, , Citation Ali Mohammed Sabur and Muayad Ahmed Rdaiaan 2021 J. Phys.: Conf. Ser. 1879 022056 DOI 10.1088/1742-6596/1879/2/022056

1742-6596/1879/2/022056

Abstract

In this study, we synthesized a series of benzimidazole compounds containing. 1,3,4-thiadiazole ring from many reaction steps. The obtained benzimidazole series were characterized by melting point, Data from FT-IR and 1H-13C-NMR and In vitro screening of antibacterial activity against strains of selected pathogenic Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative (Acinetobacter baumannii, Pseudomonas aeruginosa) bacteria relative to (Amoxicillin) and (Ciprofloxacin) as standard antibacterial agents has shown high pharmacological activity.

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10.1088/1742-6596/1879/2/022056