Focus on the Physics of Cancer

Figure
Figure. Spinodal decompostion in a two-phase mixture model giving labyrinth clusters of cancerous (green) and healthy (blue) cells. Cell–cell adhesion and nutrient consumption originate this microstructural patterning, which is compared to clinical observations in skin tumor lesions. Taken from Chatelain et al 2011 New J. Phys. 13 115013

Robijn Bruinsma, University of California, Los Angeles, USA
Jean-François Joanny, Curie Institute, Paris, France
Josef A Käs, University of Leipzig, Germany

The growth and proliferation of cancer have traditionally been investigated from a molecular–genetic–biological perspective. Increasingly, however, the mechanisms underpinning the development of cancer cells and tumours are being illuminated from a physical point of view. This focus issue aims to bring together some of the cutting-edge work in the field, in order to illustrate the current state of the art. We hope that you find the work featured in this issue to be interesting and of use in your research.

NJP board member, Cecile Sykes, has recently given an interview on 'the physics of cancer'. Listen to it here.

The articles listed below form the complete collection.











Open access
Focus on the physics of cancer

Thomas Risler 2015 New J. Phys. 17 055011

Open access
Extending the molecular clutch beyond actin-based cell motility

Svitlana Havrylenko et al 2014 New J. Phys. 16 105012

Open access
The effect of neighboring cells on the stiffness of cancerous and non-cancerous human mammary epithelial cells

Xinyi Guo et al 2014 New J. Phys. 16 105002

Open access
Compression stiffening of brain and its effect on mechanosensing by glioma cells

Katarzyna Pogoda et al 2014 New J. Phys. 16 075002

Open access
Non-invasive characterization of intracranial tumors by magnetic resonance elastography

M Simon et al 2013 New J. Phys. 15 085024

Open access
Morphological instabilities of stratified epithelia: a mechanical instability in tumour formation

Thomas Risler and Markus Basan 2013 New J. Phys. 15 065011

Open access
Modeling of nanotherapeutics delivery based on tumor perfusion

Anne L van de Ven et al 2013 New J. Phys. 15 055004

Open access
Accelerated tumor invasion under non-isotropic cell dispersal in glioblastomas

Joaquim Fort and Ricard V Solé 2013 New J. Phys. 15 055001

Open access
Influence of microfluidic shear on keratin networks in living cells

Jens-Friedrich Nolting and Sarah Köster 2013 New J. Phys. 15 045025

Open access
Metastatic cancer cells tenaciously indent impenetrable, soft substrates

R Kristal-Muscal et al 2013 New J. Phys. 15 035022

Open access
Quantifying stretching and rearrangement in epithelial sheet migration

Rachel M Lee et al 2013 New J. Phys. 15 025036

Open access
On the existence and strength of stable membrane protrusions

Juliane Zimmermann and Martin Falcke 2013 New J. Phys. 15 015021

Open access
Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

Michael J Mitchell and Michael R King 2013 New J. Phys. 15 015008

Open access
A multiphase model for three-dimensional tumor growth

G Sciumè et al 2013 New J. Phys. 15 015005

Open access
The integrin alphav beta3 increases cellular stiffness and cytoskeletal remodeling dynamics to facilitate cancer cell invasion

Claudia Tanja Mierke 2013 New J. Phys. 15 015003

Open access
The impact of jamming on boundaries of collectively moving weak-interacting cells

Kenechukwu David Nnetu et al 2012 New J. Phys. 14 115012

Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones

Dirk Drasdo and Stefan Hoehme 2012 New J. Phys. 14 055025

Isotropic stress reduces cell proliferation in tumor spheroids

Fabien Montel et al 2012 New J. Phys. 14 055008

Spatial structure increases the waiting time for cancer

Erik A Martens et al 2011 New J. Phys. 13 115014

Emergence of microstructural patterns in skin cancer: a phase separation analysis in a binary mixture

C Chatelain et al 2011 New J. Phys. 13 115013

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