In this research, Nano-metakaolin was used to investigate the achievable prospects to enhance asphalt mixture properties. The aim of this study was to evaluate the effect of adding Nano-Metakaolin on the properties of asphalt mix and comparing it with the local and international requirements, besides identifying the optimum percent of NMK to be incorporated in the hot mix asphalt. As a modifier to the bitumen several percentages of Nano-Metakaolin was used i.e. 1, 2, 4, 8, 16 and 20% by weight of bitumen. Modified asphalt binders were subjected to physical and conventional tests which were penetration, kinematic viscosity, softening point, and ductility. From these tests, optimum Nano-Metakaolin was 16%. After obtaining the optimum Nano-Metakaolin, two sets of asphalt concrete mixtures were prepared, the first was with the pure asphalt (control mixture) and the second was with the optimum Nano-Metakaolin i.e. 16% (modified mixes). The control and modified mixtures have been evaluated based on experimental tests, such as Marshall Stability (MS), Marshall flow, Marshall stiffness, Indirect Tensile Strength (ITS) and Index of Retained Strength (IRS). The results for these tests indicated an improvement in the mechanical proprieties i.e. increased Marshall Stability, Indirect Tensile Strength (ITS), and index of retained strength. As a final result, the use of (16%) Nano-metakaolin by weight of asphalt enhanced asphalt concrete properties and produce durable mixtures for highway construction.