We examined a PET detector consisting of an LYSO array coupled to a
4 × 4 array of large-size Geiger-mode avalanche photodiode (GAPD).
The GAPD coupled to 3 mm × 3 mm × 20 mm LYSO pixel crystal
has been investigated for possible use as an MR-compatible PET photosensor.
Primary characteristics of a PET detector, such as energy resolution and
coincidence timing resolution were measured. Gain variation, count
uniformity, and count estimation error of 4 × 4 array of LYSO-GAPD
were measured to evaluate the performance parameters relevant for PET
imaging. The energy resolution and coincidence timing resolution with 511
keV gamma rays were 18.5 ± 0.7% and 1.6 ns, respectively. The gain
variation, count uniformity for all 16 channels were 1.3:1 and 1.3:1,
respectively. The count estimation error between adjacent channels measured
with an LYSO connected to a GAPD pixel was negligible (0.24 ±
0.04%). Long-term stability results show that there was no significant
change in the photopeak position, energy resolution and count rate for 20
days. Cable lengths up to 300 cm, used between the GAPD and preamplifier,
did not affect photopeak position and energy resolution. The performance of
the LYSO-GAPD detector inside the MRI exhibited no significant change
compared to that measured outside the MRI. The MR images acquired with and
without the operating LYSO-GAPD detector located on top of the RF coil
showed no considerable degradation in image quality. These results
demonstrate the feasibility of using the LYSO-GAPD detector as PET
photosensors, which could be used for MR compatible PET development.