The pressure dependence of the lattice constant of silicon was observed by the X-ray diffraction powder method under pressures up to 65 kbar generated by a cubic anvil press, where kerosene, isopropyl alcohol and a 1 : 1 -volume mixture of pentane and isopentane were used as pressure transmitting liquid media. The observed diffraction lines (111), (220) and (311) indicate that as long as the media maintain the liquid state, the pressure dependence of the lattice constant is in agreement with that obtained by bulk compression. Once the media starts to solidify with pressure, the dependence deviates and the lattice contraction becomes larger to have such values as those obtained when a solid pressure medium is employed. Corresponding to the solidification, the line widths of (220) and (311) become larger remarkably, suggesting the possibility of the lattice deformation in the orthorhombic structure.