Abstract
MXenes are an emerging class of 2D layered nanomaterials that provide large surface area, hydrophilicity, high ion transport properties, low diffusion barrier, biocompatibility, and ease of surface functionalization. Due to their unique features, MXenes have gained substantial attention in fields such as batteries and supercapacitors and their application in chemical and biological sensors is growing. Their composition and layered structure make MXenes particularly attractive for biosensing applications. This presentation is focused on the synthesis and characterization of MXene-CeO2 nanocomposite for glucose sensing. The developed MXene-nanoparticles hybrid was then used as a transducer surface and supporting material for the immobilization of enzymes in an electrochemical biosensor setup. The incorporation of MXene into the sensor design enhanced the efficiency of the developed biosensor in terms of facilitating charge transfer and maximizing cerium oxide and biomolecule loading. Opportunities for developing wearable sensors and systems with integrated biomolecule recognition will be highlighted.