Abstract
Scanning tunneling microscopy (STM) has greatly contributed to the field of surface science over the past two decades. Today, the STM is a powerful instrument contributing to the study of emerging research directions in nanoscience. With a suitable choice of STM manipulations combined with tunneling spectroscopy and imaging, experiments can be tailored to investigate electronic, structural, and mechanical properties specific to atoms, molecules, and nanosystems. In this article, the basic STM manipulation schemes are explained and some examples of STM manipulation experiments related to the atomistic constructions and mono-molecular devices are described.