Evaluation of a Bio Nano-Sensing Probe Fabricated by Focused-Ion-Beam Chemical Vapor Deposition for Single Organelle Analyses

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Published 6 December 2007 • Copyright (c) 2007 The Japan Society of Applied Physics
, , Citation Reo Kometani et al 2007 Jpn. J. Appl. Phys. 46 7963 DOI 10.1143/JJAP.46.7963

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Author affiliations

1 Graduate School of Science, University of Hyogo, 3-1-2 Koto, Kamigori, Ako, Hyogo 678-1205, Japan

2 CREST JST, Japan Science and Technology Agency, Kawaguchi Center Building, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan

3 JSPS Research Fellow, Japan Society for the Promotion of Science, 8 Ichibancho, Chiyoda-ku, Tokyo 102-8472, Japan

4 SII NanoTechnology Inc., 36-1 Takenoshita, Oyama, Shizuoka 410-1393, Japan

Dates

  1. Received 19 July 2007
  2. Accepted 29 August 2007
  3. Published

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Abstract

It is necessary to manipulate and analyze single cells and organelles with high accuracy for a deeper understanding of their biological phenomena. For this purpose, bio nano-tools are very useful. We fabricated a bio nano-sensing probe by using focused-ion-beam chemical vapor deposition (FIB-CVD) and evaluated it using a cell of an Egeria densa leaf. We found that the probe functions as a measurement electrode. This indicates that the bio nano-sensing probe is useful for single organelle analyses.

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10.1143/JJAP.46.7963