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Comparison of DNA damage level in irradiated blood cells of mouse, frog and human

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Published under licence by IOP Publishing Ltd
, , Citation I Y Mitroshina et al 2019 IOP Conf. Ser.: Mater. Sci. Eng. 487 012016 DOI 10.1088/1757-899X/487/1/012016

1757-899X/487/1/012016

Abstract

Here, we present the comparative studies of DNA damage induced by X-ray irradiation in vitro in mouse, frog and human blood cells and assessed by the "comet test" (alkaline version). We showed that, in contrast to mouse and human cells, DNA repair processes in frog blood cells are not completed by 60 minutes of the post-radiation period. The results suggest that frogs can be used as indicators of environmental radiation pollution. In this regard, additional experiments are needed to assess the different types of external and internal exposure of animals.

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10.1088/1757-899X/487/1/012016