Abstract
Objective: The molecular mechanism of Oxalis corniculata (L.) in the treatment of hepatitis was studied by network pharmacology. Methods: The active ingredients of that were screened using network pharmacology. The "drug-active ingredient-target-disease" network was constructed. The signal pathway and biological process of the target was analysed by DAVID database. Results: Screen out 8 active compounds and 30 potential targets, the target proteins are TP53, AKT1, ALB, and IL6, respectively. 42 biological processes and 39 signaling pathways were screened. It exerts anti-hepatic effects by regulating signaling pathways (such as cancer pathways, hepatitis B and PI3K-Akt signaling pathways). Conclusion: Network pharmacology provides new ideas and methods for revealing the anti-hepatic mechanism of Oxalis corniculata (L), and provides scientific basis for further research and development of Oxalis corniculata (L).
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