Abstract
Decreased quality of spermatozoa can occur because of the formation of free radicals resulting from ethanol induction. Salam [Syzygium polyanthum (Wight.) Walp.] leaves have been reported to have antioxidant activity. However, it is not known whether this antioxidant activity can overcome the decline in spermatozoa motility. Therefore, a study was conducted to investigate the effects of ethanol extracts obtained from salam leaves on spermatozoa motility in ethanol-induced mice (Mus musculus L.). Animals were divided into 5 groups. The normal control group (KK1) was not treated and the treatment control group (KK2) was administered with 0.5 % carboxy methyl cellulose (CMC) and ethanol (40 % v/v) at 2.8 g/kg body weight (bw). Ethanolic extracts of salam leaves at doses of 43.75, 87.5 and 175 mg/kg bw were orally administered into the mice in treated group 1 (KP1), treated group 2 (KP2), and treated group 3 (KP3), respectively. All treated mice were induced daily by ethanol per oral (p.o) at a dose of 2.8 g/kg bw (40 % v/v). The treatment was given for 20 consecutive days. The results of LSD testing showed that ethanol extracts of salam leaves resulted in significantly (P < 0.05) higher percentages of spermatozoa motility. Compared to the mice of the KK2 group (44.88 % ± 3.40 %), the spermatozoa motility of all treated groups (KP1 56.97 % ± 2.66 %; KP2 58.19 % ± 5.33 %; KP3 53.77 % ± 4.00 %) showed higher percentages of motility.
Export citation and abstract BibTeX RIS
Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.