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Genetic diversity of feline leukemia virus

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Published under licence by IOP Publishing Ltd
, , Citation A K Komina et al 2019 IOP Conf. Ser.: Earth Environ. Sci. 315 042038 DOI 10.1088/1755-1315/315/4/042038

1755-1315/315/4/042038

Abstract

Feline Leukemia Virus (FeLV) belongs to retrovirus family, causing various proliferative and immunosuppressive diseases in felines. There are two forms of FeLV: endogenous (enFeLV) and exogenous (exFeLV), the latter has 4 subgroups: A, B, C and T with different receptor specificity. The FeLV-A is the most abundant transmissive form. The FeLVB emerged as a recombinant between provirus FeLV-A and endogenous virus of domestic cats. The FeLV-C appeared as a result of accumulation of mutations in the env FeLV-A gene. The chimeric FeLV-T virus was obtaind as recombination event between 61E and 61C viruses. This review also covers two new recently described subgroups - FeLV-D и TG35.

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10.1088/1755-1315/315/4/042038