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The H2O2 treated agarose compositing with gelatin for skin repair

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, , Citation Tianyi Tang et al 2021 J. Phys.: Conf. Ser. 1980 012016 DOI 10.1088/1742-6596/1980/1/012016

1742-6596/1980/1/012016

Abstract

This paper presented that the H2O2 treated agarose (abbr. AG) was composited with gelatin (abbr.Gel) as gel-like polymeric mixture for skin cut repair. The low molecular weight AG was prepared by H2O2 treatment for certain intervals. The time of AG gelling might be tested by scattered light turbidimeter and its mechanical properties were evaluated. The degraded AG mixing with Gel was sprayed to cover rabbit lesion site. AG/Gel mixing gel had good biocomptability and could repair rabbit skin wound without liquid exudation and bacterium infection. H&E staining results disclosed that type I collagen and other extracelluar matrix in the repaired site have same with the original skin. The degraded AG mixing with Gel gels have potential as wound dressings.

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10.1088/1742-6596/1980/1/012016