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Synthesis of some new heterocyclic compounds derived from p-chlorobenzoylchloride and investigation of biological effectiveness

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Published under licence by IOP Publishing Ltd
, , Citation R M Abdul-Amir et al 2021 J. Phys.: Conf. Ser. 1853 012009 DOI 10.1088/1742-6596/1853/1/012009

1742-6596/1853/1/012009

Abstract

1,3-Oxazole-5-one blends 2(a-c) have been set up by cyclization of compound (1) with aromatic aldehyde auxiliaries. The starting compound (1) was expeditiously procured by the reaction of 4-chlorobenzoylchloride with aminoacetic acid. Blends 2(a-c) were changed over into a grouping of subordinates by the reaction with ethylenediamine to masterminded 3(a-c) by then blends 3(a-c) reaction with aromatic aldehydes subsidiaries to organized 4(a-c). Each new compound was depicted by Proton atomic attractive reverberation (1H-NMR), Fourier changes infrared spectroscopy (FTIR), and Ultraviolet (UV) spectroscopy.

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10.1088/1742-6596/1853/1/012009