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Cytotoxic activity of methanol extraction of Avicennia marina and taurin in the HeLa cancer cells

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, , Citation S Andriani et al 2021 J. Phys.: Conf. Ser. 1751 012045 DOI 10.1088/1742-6596/1751/1/012045

1742-6596/1751/1/012045

Abstract

The aim of study was to determine any anticancer potential from Avicennia marina leaf extract compare to taurine on cytotoxic and anti-proliferation activities against HeLa cervical cancer cell line by using the MTT method (3-(4, 5-dimethylthiazol-2-yl))-2, 5-diphenyltetrazolium bromide). The results indicated that methanol extraction of A. marina leaf as well as taurine did have cytotoxic and anti-proliferation effects on HeLa cell line with IC50 values of 321 ppm and 603 ppm 1000 ppm. While the doubling time value for anti-proliferation of A. marina leaf methanol extraction and taurine showed higher values than the control group (72.19 hours).

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