The association between male serum anti-mullerian hormone and the outcomes of intracytoplasmic sperm injection

To evaluate the correlation between male serum anti-mullerian hormone and ICSI outcomes ( fertilization rate, cleveage rate, quality of embryos and pregnancy rate ). The type of study was controlled randomized study on fifty five infertile couples undergoing ICSI procedure at fertility center in Al-Sadder medical city in Al Najaf Al Ashraf. The research was included two groups are unexplained (n=24) and male factor infertility ( n=31)who underwent intracytoplasmic sperm injection programme. blood samples were taken from husbands to assessment of anti-mullerian hormone at day of retrieval of follicles. The results of ICSI were reported in both two groups. The correlation between male serum anti-mullerian hormone with fertilization rate, cleavege rate, and quality of embryos was studied. The current research results were revealed significant increase ( P <0.001), in concentration of male serum anti-mullerian hormone in unexplained group (7.29 ± 0.73) compared to male factor (2.36 ± 0.19 ) group. good quality embryos had significant increase (P value0.053)in unexplained group (5.70 ± 0.94) compared to male factor group(3.70 ± 0.5). Pregnancy rate was also found to be not significantly differed but the higher percentage of pregnancy (32.3%) occurred in male factor group compared to unexplained group(25%).There was positive correlation (r=0.293 p=0.03 ) between good quality embryos and male serum anti-mullerian hormone. Results of this study showed found positive correlation between male serum anti-mullerian hormone and good embryos which may lead to improvement in pregnancy rates.