Abstract
A novel radiochromic PRESAGE sheet (Heuris Inc.) with variable thickness of 1-3 mm has been developed to provide 2D dosimetry. It can also be used for patient surface dosimetry or as a tool for patient-specific QA (PSQA) in 3D dosimetry. Its softness and flexibility to conform with the patient's skin make this product advantageous for future clinical applications. This study presents a comprehensive investigation into the PRESAGE sheet's dosimetric accuracy at different scanning times and its potential use for clinical applications. For the characterization of the dosimeter, temporal stability of dose rate, energy dependence, dose linearity, beam profile, and dose distribution measurements were investigated by irradiating a single sheet of PRESAGE with different doses and energies while scanning the sheet with an Epson 11000XL high-resolution scanner at different time intervals following its irradiation. Additionally, two clinical applications, including PSQA and surface dose measurement, were conducted and were compared to dosimeters currently used for clinical applications. For QA measurement, a stack of PRESAGE sheets, with EBT3 films sandwiched in-between, was used to measure the dose distribution of a pancreas SBRT treatment plan at different depths. For surface dose measurement, PRESAGE sheets, EBT3 films, and OSLDs were placed on the surface of an anthropomorphic phantom to measure the skin dose of a modulated treatment fields. When the stack of PRESAGE sheets were scanned within a period of two hours following its irradiation, the dosimeter exhibits a stable linear response to dose with negligible dose rate and energy dependence. In addition to its temporal stability, the dosimeter can provide accurate relative dose measurements comparable to those exhibited by EBT3 films. In the application of PSQA, when compared with EBT3 films using gamma test with a 2%/2 mm criteria, PRESAGE sheets have a passing rate of 99.7% measured at the isocenter and 99.1% in application of surface dose measurements. This study demosntrates the dosimetric characteristics and the potential use of a novel dosimeter, PRESAGE sheets.
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