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The following article is Open access

Collective Langevin dynamics of flexible cytoskeletal fibers

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Published 30 November 2007 Published under licence by IOP Publishing Ltd
, , Focus on Physics of the Cytoskeleton Citation Francois Nedelec and Dietrich Foethke 2007 New J. Phys. 9 427 DOI 10.1088/1367-2630/9/11/427

1367-2630/9/11/427

Abstract

We develop a numerical method to simulate mechanical objects in a viscous medium at a scale where inertia is negligible. Fibers, spheres and other voluminous objects are represented with points. Different types of connections are used to link the points together and in this way create composite mechanical structures. The motion of such structures in a Brownian environment is described by a first-order multivariate Langevin equation. We propose a computationally efficient method to integrate the equation, and illustrate the applicability of the method to cytoskeletal modeling with several examples.

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10.1088/1367-2630/9/11/427