T Rubin et al 2011 J. Breath Res. 5 027102 doi:10.1088/1752-7155/5/2/027102
T Rubin, T von Haimberger, A Helmke and K Heyne1
Show affiliationsWe have developed a flow-through fast liver investigation packet (FLIP) to quantitatively measure the amount of exhaled 13CO2, as a result of liver metabolization processes. The FLIP system allows investigation of every single breath in real time. Line width variations due to interactions with other gas components disturb traditional measurements and limit their sensitivity to the ppm range. Detection of the complete breath volume and the spectrally fully resolved line shape allows sensitivity in the ppb range with a standard deviation of approximately 80 ppb, a prerequisite to quantitatively analyze liver metabolization processes.
87.80.-y Biophysical techniques (research methods)
Issue 2 (June 2011)
Received 31 October 2010, accepted for publication 29 March 2011
Published 19 April 2011
T Rubin et al 2011 J. Breath Res. 5 027102