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Biological effects induced by nanosilver particles: in vivo study

Dandan Chen1, Tingfei Xi1 and Jing Bai2

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Nanosilver particles and microsilver particles were implanted into a rat's back muscle. The pathology and the local biocompatibility were observed and compared at days 7, 14, 30, 90 and 180 after implantation. A good biological effect was observed on days 7 and 14, both in rats treated with nanosilver particles and in rats treated with microsilver particles. A bad biological effect was observed at day 30, and the nanosilver-treated rats had more serious inflammation than the microsilver-treated rats.


PACS

87.50.-a Effects of electromagnetic and acoustic fields on biological systems

89.60.Ec Environmental safety

Subjects

Medical physics

Biological physics

Environmental and Earth science

Dates

Issue 3 (September 2007)

Received 26 April 2007, accepted for publication 3 May 2007

Published 30 July 2007



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