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Drug loading of nanoporous TiO2 films

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Arturo A Ayon1, Michael Cantu1,2, Kalpana Chava1,3, C Mauli Agrawal4, Marc D Feldman5, Dave Johnson6, Devang Patel5, Denes Marton5 and Emily Shi7

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COMMUNICATION

The loading of therapeutic amounts of drug on a nanoporous TiO2 surface is described. This novel drug-loading scheme on a biocompatible surface, when employed on medical implants, will benefit patients who require the deployment of drug-eluting implants. Anticoagulants, analgesics and antibiotics can be considered on the associated implants for drug delivery during the time of maximal pain or risk for patients undergoing orthopedic procedures. Therefore, this scheme will maximize the chances of patient recovery.


PACS

87.85.Qr Nanotechnologies-design

87.85.J- Biomaterials

81.05.Rm Porous materials; granular materials

Subjects

Condensed matter: structural, mechanical & thermal

Dates

Issue 4 (December 2006)

Received 21 July 2006, accepted for publication 9 August 2006

Published 25 August 2006



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