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X-ray Tomographic Microscopy at TOMCAT

F Marone1, C Hintermüller1, S McDonald1,2, R Abela1, G Mikuljan1, A Isenegger1 and M Stampanoni1,3

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Synchrotron-based X-ray Tomographic Microscopy is a powerful technique for fast non-destructive, high resolution quantitative volumetric investigations on diverse samples. At the TOMCAT (TOmographic Microscopy and Coherent rAdiology experimenTs) beamline at the Swiss Light Source, synchrotron light is delivered by a 2.9 T superbend. The main optical component, a Double Crystal Multilayer Monochromator, covers an energy range between 8 and 45 keV. The standard TOMCAT detector offers field of views ranging from 0.75×0.75 mm2 up to 12.1×12.1 mm2 with a pixel size of 0.37 μm and 5.92 μm, respectively. In addition to routine measurements, which exploit the absorption contrast, the high coherence of the source also enables phase contrast tomography, implemented with two complementary techniques (Modified Transport of Intensity approach and Grating Interferometry). Typical acquisition times for a tomogram are in the order of few minutes, ensuring high throughput and allowing for semi-dynamical investigations. Raw data are automatically post-processed online and full reconstructed volumes are available shortly after a scan with minimal user intervention.


PACS

07.85.Tt X-ray microscopes

81.70.-q Methods of materials testing and analysis

87.80.-y Biophysical techniques (research methods)

Subjects

Instrumentation and measurement

Medical physics

Biological physics

Condensed matter: structural, mechanical & thermal

Dates

Issue 1 (2009)



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