Tatyana I Aksenova et al 2007 J. Neural Eng. 4 173 doi:10.1088/1741-2560/4/3/001
Tatyana I Aksenova1,2, Vladimir V Volkovych2 and Alessandro E P Villa1,3,4
Show affiliationsThe study of EEG recordings during the interval prior to an epileptic seizure onset—the preictal period—is likely to detect changes in the ongoing brain activity consistent with seizure anticipation. A novel index of spectral instability (ISpI) based on multiple abrupt changes of EEG spectral features is presented here. Based on the analysis of control records, robust M-estimates are used to calculate the threshold and avoid false warnings. The results obtained with a small data set (three patients, ten preictal records per patient) have shown that the ISpI index provided a warning flag that anticipated the seizure onset by 13.1 (SD = 4.0) min on average.
87.19.R- Mechanical and electrical properties of tissues and organs
Issue 3 (September 2007)
Received 12 April 2006, accepted for publication 1 March 2007
Published 4 April 2007
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