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Mechanical aspects of developmental biology: perspectives On Growth and Form in the (post)-genomic age

M Shane Hutson and Xiaoyan Ma

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Simple experiments demonstrate that the development of an organism is both a genetic and a physical process. This statement is so obvious that it is seldom stated explicitly, and yet, there has been little progress toward integrating what should be complementary viewpoints. This paper focuses on the mechanical aspects of morphogenesis—highlighting those areas where mechanics and molecular genetics are converging toward a much-needed synthesis.


PACS

87.19.R- Mechanical and electrical properties of tissues and organs

87.18.Hf Spatiotemporal pattern formation in cellular populations

87.15.-v Biomolecules: structure and physical properties

87.18.Ed Cell aggregation

87.18.-h Biological complexity

Subjects

Medical physics

Biological physics

Dates

Issue 1 (March 2008)

Received 25 February 2008, accepted for publication 14 March 2008

Published 9 April 2008

 
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