Joel Stavans and Amos Oppenheim 2006 Phys. Biol. 3 R1 doi:10.1088/1478-3975/3/4/R01
Joel Stavans1 and Amos Oppenheim2
Show affiliationsBacteria, like eukaryotic organisms, must compact the DNA molecule comprising their genome and form a functional chromosome. Yet, bacteria do it differently. A number of factors contribute to genome compaction and organization in bacteria, including entropic effects, supercoiling and DNA–protein interactions. A gamut of new experimental techniques have allowed new advances in the investigation of these factors, and spurred much interest in the dynamic response of the chromosome to environmental cues, segregation, and architecture, during both exponential and stationary phases. We review these recent developments with emphasis on the multifaceted roles that DNA–protein interactions play.
87.15.K- Molecular interactions; membrane-protein interactions
87.16.Ka Filaments, microtubules, their networks, and supramolecular assemblies
Issue 4 (December 2006)
Received 20 September 2006, accepted for publication 30 November 2006
Published 22 December 2006
Joel Stavans and Amos Oppenheim 2006 Phys. Biol. 3 R1
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