David Zanuy et al 2006 Phys. Biol. 3 S80 doi:10.1088/1478-3975/3/1/S08
From peptide-based material science to protein fibrils: discipline convergence in nanobiology
David Zanuy1, Ruth Nussinov2,3 and Carlos Alemán1
Show affiliationsThis paper illustrates the merits of convergence in nanobiology of two seemingly disparate fields, material science and computational biology. Traditionally, material science has been a discipline involving design and fabrication of synthetic polymers consisting of repeating units. Collaboration with synthetic organic chemists allowed design of new polymers, with a range of altered conformations. Yet, naturally occurring proteins are also materials. Their varied sequences and structures should enrich material science providing more complex shapes, scaffolds and chemical properties. For material scientists, the enhanced coverage of chemical space obtained by integrating proteins and synthetic organic chemistry through the introduction of non-natural residues allows a range of new useful potential applications.
- PACS
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87.15.B- Structure of biomolecules
87.15.Cc Folding: thermodynamics, statistical mechanics, models, and pathways
- Subjects
- Dates
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Issue 1 (March 2006)
Received 3 January 2006, accepted for publication 17 March 2006
Published 31 March 2006
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From peptide-based material science to protein fibrils: discipline convergence in nanobiology
David Zanuy et al 2006 Phys. Biol. 3 S80
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