Filipe Tostevin and Martin Howard 2006 Phys. Biol. 3 1 doi:10.1088/1478-3975/3/1/001
A stochastic model of Min oscillations in Escherichia coli and Min protein segregation during cell division
Filipe Tostevin and Martin Howard
Show affiliationsThe Min system in Escherichia coli directs division to the centre of the cell through pole-to-pole oscillations of the MinCDE proteins. We present a one-dimensional stochastic model of these oscillations which incorporates membrane polymerization of MinD into linear chains. This model reproduces much of the observed phenomenology of the Min system, including pole-to-pole oscillations of the Min proteins. We then apply this model to investigate the Min system during cell division. Oscillations continue initially unaffected by the closing septum, before cutting off rapidly. The fractions of Min proteins in the daughter cells vary widely, from 50%–50% up to 85%–15% of the total from the parent cell, suggesting that there may be another mechanism for regulating these levels in vivo.
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Issue 1 (March 2006)
Received 26 August 2005, accepted for publication 7 November 2005
Published 29 November 2005
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A stochastic model of Min oscillations in Escherichia coli and Min protein segregation during cell division
Filipe Tostevin and Martin Howard 2006 Phys. Biol. 3 1
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Photo cells: the valves which operate by light
C C Paterson 1932 J. Sci. Instrum. 9 33
-
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A El Badia et al 2005 Inverse Problems 21 1121
-
Sr2RuO4: an electronic analogue of 3He?
T M Rice and M Sigrist 1995 J. Phys.: Condens. Matter 7 L643
-
The canonical connection of a bi-Lagrangian manifold
F Etayo Gordejuela and R Santamaría 2001 J. Phys. A: Math. Gen. 34 981
-
Charge exchange in atom-surface scattering and sputtering processes
E A Garcia et al 1993 J. Phys.: Condens. Matter 5 A279
-
A minimal stochastic model for influenza evolution
F Tria et al J. Stat. Mech. (2005) P07008
-
Magnetic needles and superparamagnetic cells
H C Bryant et al 2007 Phys. Med. Biol. 52 4009
-
Self-assembly of information in networks
M. Rosvall and K. Sneppen 2006 Europhys. Lett. 74 1109
-
The VLA-COSMOS Survey. I. Radio Identifications from the Pilot Project
E. Schinnerer et al. 2004 The Astronomical Journal 128 1974
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