Robert W Applegate Jr et al 2007 J. Opt. A: Pure Appl. Opt. 9 S122 doi:10.1088/1464-4258/9/8/S03
Robert W Applegate Jr1, Dawn N Schafer1, Wafa Amir1, Jeff Squier1, Tor Vestad2, John Oakey2 and David W M Marr3
Show affiliationsExpanding interest in microfluidic techniques for biomedical applications has driven the recent need for micro-integrated optics capable of both traditional characterization and emerging optical manipulation techniques. We discuss here how ultrafast laser micromachining can be used to create optical waveguides directly within microfluidic systems. We then utilize this fabrication approach to create a unique microfluidic platform for optical characterization and sorting of cells and particles. This new platform employs optically fabricated waveguides to scatter and refract light from individual particles, allowing accurate in situ size detection and sorting within a microfluidic channel.
87.80.Fe Micromanipulation of biological structures
42.82.Et Waveguides, couplers, and arrays
85.85.+j Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
42.82.Cr Fabrication techniques; lithography, pattern transfer
Instrumentation and measurement
Issue 8 (August 2007)
Received 15 January 2007, accepted for publication 2 March 2007
Published 23 July 2007
Robert W Applegate Jr et al 2007 J. Opt. A: Pure Appl. Opt. 9 S122
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