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Deutsche Physikalische Gessellschaft IOP Institute of Physics

Collective Langevin dynamics of flexible cytoskeletal fibers

Focus on Physics of the Cytoskeleton

Francois Nedelec1 and Dietrich Foethke

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Part of Focus on Physics of the Cytoskeleton

We develop a numerical method to simulate mechanical objects in a viscous medium at a scale where inertia is negligible. Fibers, spheres and other voluminous objects are represented with points. Different types of connections are used to link the points together and in this way create composite mechanical structures. The motion of such structures in a Brownian environment is described by a first-order multivariate Langevin equation. We propose a computationally efficient method to integrate the equation, and illustrate the applicability of the method to cytoskeletal modeling with several examples.


PACS

87.18.Ed Cell aggregation

05.40.Jc Brownian motion

87.17.Aa Modeling, computer simulation of cell processes

Subjects

Biological physics

Statistical physics and nonlinear systems

Dates

Issue 11 (November 2007)

Received 14 June 2007

Published 30 November 2007



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