We present a series of measurements on nine single Cooper-pair boxes (SCBs), where the charging energy, E_C, and the Josephson coupling energy, E_J, have been varied. We have investigated both the ground state properties of the SCBs and their quantum coherent properties. The state of the SCBs could be manipulated by an external gate voltage and the charge was measured by coupling it capacitatively to a radio-frequency single-electron-transistor (RF-SET). By ramping the gate voltage and simultaneously measuring the charge of the SCBs using the RF-SET, we could measure the Coulomb staircases of the SCBs. For sufficiently low E_C the SCBs showed a fully 2e periodic Coulomb staircase. For samples with higher E_C the staircase showed a short step for odd number of charges indicating quasi-particle 'poisoning'. However, if E_C was not too large, the short step could be removed by applying a parallel magnetic field. We attribute this effect to a stronger suppression of the superconducting energy gap in the reservoir than in the box. Using microwave spectroscopy we have determined E_C and E_J for the SCBs. These values agree well with the shape of the Coulomb staircases which we measure. For a limited range of gate voltage, the SCBs were found to behave as model two-level quantum-mechanical systems. A non-adiabatic change in the induced island charge was used to bring two charge states into resonance. The resulting time evolution showed clear charge oscillations between the ground and excited state, with an amplitude above 70% and a frequency given by the energy level separation divided by Planck's constant. These oscillations had a longest coherence time of T₂ = 9 ns, at a point where the pure charge states are degenerate. The coherence time at this point was found to be limited by the relaxation rate. Away from the charge degeneracy point, the coherence time was limited by the pure dephasing rate. The dependence of T₂ on gate charge suggested that low frequency fluctuators were the main source of dephasing away from the degeneracy point.