Delai Chen et al 2009 New J. Phys. 11 075017 doi:10.1088/1367-2630/11/7/075017
Using TIRF microscopy to quantify and confirm efficient mass transfer at the substrate surface of the chemistrode
Focus on Micro- and NanofluidicsDelai Chen, Wenbin Du and Rustem F Ismagilov1
Show affiliationsPart of Focus on Micro- and Nanofluidics
This paper describes experiments for characterizing mass transfer at the hydrophilic surface of the substrate in a chemistrode. The chemistrode uses microfluidic plugs to deliver pulses of chemicals to a substrate with high temporal resolution, which requires efficient mass transfer between the wetting layer and the hydrophilic surface of the substrate. Here, total internal reflection fluorescence microscopy (TIRFM) was used to image the hydrophilic surface of the substrate as plugs were made to flow over it. The surface of the substrate was rapidly saturated with a fluorescent dye as the fluroesecent plugs passed over the substrate, confirming effective mass transfer between the wetting layer and the surface of the substrate. The dynamics of saturation are consistent from cycle to cycle, indicating that the chemistrode can stimulate surfaces with high reproducibility. The number of plugs required to reach 90% saturation of the hydrophilic surface of the substrate, 
(90%), only weakly depended on experimental conditions (the Péclet number or the capillary number). Furthermore, over a wide range of operating conditions, (90%) was less than 4. These results are useful for improving the chemistrode and for understanding other phenomena that involve diffusional transfer in multiphase or recirculating flows near surfaces.
- PACS
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85.85.+j Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
82.65.+r Surface and interface chemistry; heterogeneous catalysis at surfaces
47.61.Fg Flows in micro-electromechanical systems (MEMS) and nano-electromechanical systems (NEMS)
- Subjects
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Surfaces, interfaces and thin films
- Dates
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Issue 7 (July 2009)
Received 20 January 2009
Published 31 July 2009
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Using TIRF microscopy to quantify and confirm efficient mass transfer at the substrate surface of the chemistrode
Delai Chen et al 2009 New J. Phys. 11 075017
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