E M Cherry and F H Fenton 2008 New J. Phys. 10 125016 doi:10.1088/1367-2630/10/12/125016
Visualization of spiral and scroll waves in simulated and experimental cardiac tissue
Focus on Visualization in PhysicsE M Cherry and F H Fenton
Show affiliationsPart of Focus on Visualization in Physics
The heart is a nonlinear biological system that can exhibit complex electrical dynamics, complete with period-doubling bifurcations and spiral and scroll waves that can lead to fibrillatory states that compromise the heart's ability to contract and pump blood efficiently. Despite the importance of understanding the range of cardiac dynamics, studying how spiral and scroll waves can initiate, evolve, and be terminated is challenging because of the complicated electrophysiology and anatomy of the heart. Nevertheless, over the last two decades advances in experimental techniques have improved access to experimental data and have made it possible to visualize the electrical state of the heart in more detail than ever before. During the same time, progress in mathematical modeling and computational techniques has facilitated using simulations as a tool for investigating cardiac dynamics. In this paper, we present data from experimental and simulated cardiac tissue and discuss visualization techniques that facilitate understanding of the behavior of electrical spiral and scroll waves in the context of the heart. The paper contains many interactive media, including movies and interactive two- and three-dimensional Java applets*.
- Footnote
- PACS
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87.61.Tg Clinical applications
87.19.R- Mechanical and electrical properties of tissues and organs
- Subjects
- Dates
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Issue 12 (December 2008)
Received 17 October 2008
Published 1 December 2008
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Visualization of spiral and scroll waves in simulated and experimental cardiac tissue
E M Cherry and F H Fenton 2008 New J. Phys. 10 125016
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