Ainara Garde et al 2010 Physiol. Meas. 31 979 doi:10.1088/0967-3334/31/7/008
Ainara Garde1, Rico Schroeder2, Andreas Voss2, Pere Caminal1, Salvador Benito3 and Beatriz F Giraldo1
Show affiliationsThe process of discontinuing mechanical ventilation is called weaning and is one of the most challenging problems in intensive care. An unnecessary delay in the discontinuation process and an early weaning trial are undesirable. This study aims to characterize the respiratory pattern through features that permit the identification of patients' conditions in weaning trials. Three groups of patients have been considered: 94 patients with successful weaning trials, who could maintain spontaneous breathing after 48 h (GSucc); 39 patients who failed the weaning trial (GFail) and 21 patients who had successful weaning trials, but required reintubation in less than 48 h (GRein). Patients are characterized by their cardiorespiratory interactions, which are described by joint symbolic dynamics (JSD) applied to the cardiac interbeat and breath durations. The most discriminating features in the classification of the different groups of patients (GSucc, GFail and GRein) are identified by support vector machines (SVMs). The SVM-based feature selection algorithm has an accuracy of 81% in classifying GSucc versus the rest of the patients, 83% in classifying GRein versus GSucc patients and 81% in classifying GRein versus the rest of the patients. Moreover, a good balance between sensitivity and specificity is achieved in all classifications.
87.80.-y Biophysical techniques (research methods)
07.05.Mh Neural networks, fuzzy logic, artificial intelligence
Issue 7 (July 2010)
Received 11 January 2010, accepted for publication 12 May 2010
Published 15 June 2010
Ainara Garde et al 2010 Physiol. Meas. 31 979
Ryan J Halter et al 2009 Physiol. Meas. 30 S121
Amit J Nimunkar and John G Webster 2009 Physiol. Meas. 30 101
Andy Adler et al 2008 Physiol. Meas. 29 S101
Xiao Hu et al 2008 Physiol. Meas. 29 459
Andy Adler et al 2007 Physiol. Meas. 28 S1
Yednek Asfaw and Andy Adler 2005 Physiol. Meas. 26 S175
Melissa Suter et al 2004 Physiol. Meas. 25 837
Daniel S Moran et al 2004 Physiol. Meas. 25 51
Andy Adler 2004 Physiol. Meas. 25 227