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Effect of confounding factors on blood pressure estimation using pulse arrival time

Jung Soo Kim1, Ko Keun Kim1, Hyun Jae Baek2 and Kwang Suk Park3

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Two confounding factors were selected and analyzed in blood pressure estimation using pulse arrival time (PAT) for each individual. The heart rate was used as the confounding factor for the cardiac cycle, and the duration from the maximum derivative point to the dicrotic peak (TDB) in the photoplethysmogram was used as another confounding factor representing arterial stiffness. By considering these factors with PAT in multiple regression analysis, the performance of blood pressure estimation is enhanced significantly in the diastolic phase as well as in the systolic phase. The reproducibility of this method was also validated with formerly obtained regression equations from the training set. The correlation between estimated and measured blood pressure decreased a little, but the validity was still maintained (r cong 0.8). This shows the value of the method in non-intrusive blood pressure estimation for individual patients and may be useful for various applications.


PACS

87.80.-y Biophysical techniques (research methods)

87.19.U- Hemodynamics

87.19.R- Mechanical and electrical properties of tissues and organs

02.70.Rr General statistical methods

87.63.L- Visual imaging

47.63.Cb Blood flow in cardiovascular system

Subjects

Fluid dynamics

Computational physics

Instrumentation and measurement

Medical physics

Biological physics

Dates

Issue 5 (May 2008)

Received 7 January 2008, accepted for publication 4 April 2008

Published 7 May 2008



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