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Flow–area relationship in internal carotid and vertebral arteries

J R Cebral1, M A Castro1, C M Putman2 and N Alperin3

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Subject-specific computational and experimental models of hemodynamics in cerebral aneurysms require the specification of physiologic flow conditions. Because patient-specific flow data are not always available, researchers have used 'typical' or population average flow rates and waveforms. However, in order to be able to compare the magnitude of hemodynamic variables between different aneurysms or groups of aneurysms (e.g. ruptured versus unruptured) it is necessary to scale the flow rates to the area of the inflow artery. In this work, a relationship between flow rates and vessel areas is derived from phase-contrast magnetic resonance measurements in the internal carotid arteries and vertebral arteries of normal subjects.


PACS

87.19.U- Hemodynamics

87.19.L- Neuroscience

87.61.Tg Clinical applications

87.19.R- Mechanical and electrical properties of tissues and organs

Subjects

Medical physics

Biological physics

Dates

Issue 5 (May 2008)

Received 6 November 2007, accepted for publication 10 April 2008

Published 7 May 2008



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