W L Woon et al 2007 Physiol. Meas. 28 335 doi:10.1088/0967-3334/28/4/001
W L Woon1,2, A Cichocki1, F Vialatte1 and T Musha3
Show affiliationsAlzheimer's disease (AD) is a degenerative disease which causes serious cognitive decline. Studies suggest that effective treatments for AD may be aided by the detection of the disease in its early stages, prior to extensive neuronal degeneration. In this paper, we propose a set of novel techniques which could help to perform this task, and present the results of experiments conducted to evaluate these approaches. The challenge is to discriminate between spontaneous EEG recordings from two groups of subjects: one afflicted with mild cognitive impairment and eventual AD and the other an age-matched control group. The classification results obtained indicate that the proposed methods are promising additions to the existing tools for detection of AD, though further research and experimentation with larger datasets is required to verify their effectiveness.
87.19.R- Mechanical and electrical properties of tissues and organs
Issue 4 (April 2007)
Received 11 October 2006, accepted for publication 12 February 2007
Published 7 March 2007
W L Woon et al 2007 Physiol. Meas. 28 335
Juergen M Lackner 2007 J. Phys.: Conf. Ser. 59 16
E Ramayya et al 2006 J. Phys.: Conf. Ser. 38 126
N Qian et al 2006 J. Phys.: Conf. Ser. 48 1238
Lifeng Wang et al 2006 J. Phys.: Conf. Ser. 38 158
J L Bona et al 1995 Nonlinearity 8 1179
Lixin Dong et al 2007 J. Phys.: Conf. Ser. 61 257
Liming Yu et al 2006 J. Phys.: Conf. Ser. 34 937
J Polesel-Maris et al 2007 J. Phys.: Conf. Ser. 61 955
S Lazare et al 2007 J. Phys.: Conf. Ser. 59 543