T Cordova-Fraga et al 2007 Physiol. Meas. 28 41 doi:10.1088/0967-3334/28/1/004
T Cordova-Fraga1,2, M Gallucci1, A Bradshaw1,3,4, B Berch1 and W O Richards1
Show affiliationsThe electrical control activity of the large intestine was recorded in six pigs using a SQUID magnetometer. The study was performed in pre- and post-colectomy/sham-colectomy conditions. The biomagnetic field associated with colonic ECA changed drastically in subjects that underwent the colectomy procedure, whereas the signal for the control animals was nearly unchanged. Power spectral analysis was used to determine the average changes of dominant frequency and amplitude between baseline versus colectomy and sham-colectomy conditions. The dominant frequency was increased by 68 ± 24% (versus 2 ± 3% in control). The amplitude was decreased by 69 ± 24% (versus 13 ± 17% in control). This is the first study of transabdominal magnetic fields associated with colonic ECA, suggests some of the side effects generated in colectomy surgery and shows the utility of the biomagnetic technique in studies of the large intestine.
87.80.-y Biophysical techniques (research methods)
87.50.C- Static and low-frequency electric and magnetic fields effects
87.19.R- Mechanical and electrical properties of tissues and organs
85.25.Dq Superconducting quantum interference devices (SQUIDs)
Issue 1 (January 2007)
Received 7 August 2006, accepted for publication 16 October 2006
Published 17 November 2006
T Cordova-Fraga et al 2007 Physiol. Meas. 28 41
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