Hyun-Jik Oh et al 2006 J. Micromech. Microeng. 16 285 doi:10.1088/0960-1317/16/2/013
Hyun-Jik Oh1, So-Hyun Kim1, Ju-Yeoul Baek1, Gi-Hun Seong2 and Sang-Hoon Lee1
Show affiliationsWe report a new technique that, in contrast to conventional methods, uses a microfluidic platform for the fabrication of polymeric microcapsules that can contain sensitive biological materials. This encapsulation process is carried out through the use of hydrodynamic phenomena (e.g., multiphase laminar flow), and 'on the fly' photopolymerization. Our method allows for the generation of microcapsules whose size can be controlled by a regulation of flow rates, and the polymerized capsule can protect fragile materials, such as cells, DNA and enzymes from harsh environments. The proposed approach is extended to the fabrication of a microcontainer that can handle small volumes of liquid. The flexibility of the method across different materials and scales is a key advantage over many existing methods.
85.85.+j Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
47.15.Rq Laminar flows in cavities
Issue 2 (February 2006)
Received 14 July 2005, in final form 7 November 2005
Published 9 January 2006
Hyun-Jik Oh et al 2006 J. Micromech. Microeng. 16 285
Yu B Golubovskii et al 2006 J. Phys. D: Appl. Phys. 39 1574
S Satake et al 2009 J. Phys.: Conf. Ser. 191 012018
Daesuk Kim et al 2002 Meas. Sci. Technol. 13 L1
W J Walker et al 1974 Phys. Med. Biol. 19 210
Khaled Abdel-Waged 2005 J. Phys. G: Nucl. Part. Phys. 31 739
O B Zaslavskii 2003 Class. Quantum Grav. 20 137
R V Chepulskii 2002 J. Phys.: Condens. Matter 14 L193
A E Curzon and A J Mascall 1965 Br. J. Appl. Phys. 16 1301
Giulio Magli 1997 Class. Quantum Grav. 14 1937