Quick search Find article
Quick search
Find article

Functional recognition imaging using artificial neural networks: applications to rapid cellular identification via broadband electromechanical response

M P Nikiforov1, V V Reukov2, G L Thompson2, A A Vertegel2, S Guo1, S V Kalinin1 and S Jesse1

Show affiliations


Functional recognition imaging in scanning probe microscopy (SPM) using artificial neural network identification is demonstrated. This approach utilizes statistical analysis of complex SPM responses at a single spatial location to identify the target behavior, which is reminiscent of associative thinking in the human brain, obviating the need for analytical models. We demonstrate, as an example of recognition imaging, rapid identification of cellular organisms using the difference in electromechanical activity over a broad frequency range. Single-pixel identification of model Micrococcus lysodeikticus and Pseudomonas fluorescens bacteria is achieved, demonstrating the viability of the method.


PACS

87.17.Ee Growth and division

87.17.Aa Modeling, computer simulation of cell processes

Subjects

Biological physics

Dates

Issue 40 (7 October 2009)

Received 22 June 2009, in final form 6 August 2009

Published 14 September 2009



Related review articles

What's this?
View review articles related to this research to gain an insight into the key trends in this subject area. Related review articles are selected based on PACS/MSC codes, and are no more than three years old.

  1. Soft particle analysis of electrokinetics of biological cells and their model systems
  2. Fabrication of a thermoresponsive cell culture dish: a key technology for cell sheet tissue engineering
  3. The hydrodynamics of swimming microorganisms

View by subject




Export








Please login to access our web services, or create an account if you don't yet have one.

You must have cookies enabled in your web browser to be able to login.

Username
Password

Forgotten your password? Get a new one here.