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The fabrication of uniform cylindrical nanoshells and their use as spectrally tunable MRI contrast agents

G Zabow1,2, S J Dodd1, J Moreland2 and A P Koretsky1

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A new form of tunable magnetic resonance imaging agent based on precisely dimensioned cylindrical magnetic nanoshells is introduced. Using top-down prepatterned substrates, the nanoshells are fabricated by exploiting what is usually regarded as a detrimental processing side-effect, namely the redeposition of material back-sputtered during ion-milling. The well-resolved nuclear magnetic resonance peaks of the resulting nanostructures attest to the nanoscale fabrication control and the general feasibility of such sputter redeposition for fabrication of a variety of self-supporting, highly monodisperse nanoscale structures.


PACS

81.07.-b Nanoscale materials and structures: fabrication and characterization

87.61.-c Magnetic resonance imaging

87.50.C- Static and low-frequency electric and magnetic fields effects

75.50.Tt Fine-particle systems; nanocrystalline materials

81.16.-c Methods of nanofabrication and processing

87.85.Qr Nanotechnologies-design

Subjects

Biological physics

Medical physics

Nanoscale science and low-D systems

Dates

Issue 38 (23 September 2009)

Received 6 June 2009, in final form 15 July 2009

Published 28 August 2009



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