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An Au/Si hetero-nanorod-based biosensor for Salmonella detection

Junxue Fu1, Bosoon Park2, Greg Siragusa2, Les Jones3, Ralph Tripp3, Yiping Zhao1 and Yong-Jin Cho4

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We present a novel and effective food-borne bacteria detection method. A hetero-structured silicon/gold nanorod array fabricated by the glancing angle deposition method is functionalized with anti-Salmonella antibodies and organic dye molecules. Due to the high aspect ratio nature of the Si nanorods, dye molecules attached to the Si nanorods produce an enhanced fluorescence upon capture and detection of Salmonella. This bio-functional hetero-nanorod detection method has great potential in the food safety industry as well as in biomedical diagnostics.


PACS

81.16.Fg Supramolecular and biochemical assembly

87.80.-y Biophysical techniques (research methods)

87.16.-b Subcellular structure and processes

87.85.Qr Nanotechnologies-design

87.64.K- Spectroscopy

Subjects

Instrumentation and measurement

Medical physics

Biological physics

Nanoscale science and low-D systems

Dates

Issue 15 (16 April 2008)

Received 19 October 2007, in final form 1 February 2008

Published 11 March 2008



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