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Carbon nanopipettes for cell probes and intracellular injection

Michael G Schrlau1, Erica M Falls2, Barry L Ziober2 and Haim H Bau1,3

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We developed integrated, carbon-based pipettes with nanoscale dimensions (CNP) that can probe cells with minimal intrusion, inject fluids into the cells, and concurrently carry out electrical measurements. Our manufacturing technique does not require cumbersome nanoassembly and is amenable to mass production. Using CNPs, we demonstrate the injection of reagents into cells with minimal intrusion and without inhibiting cell growth.


PACS

81.16.-c Methods of nanofabrication and processing

87.85.Qr Nanotechnologies-design

Subjects

Nanoscale science and low-D systems

Dates

Issue 1 (9 January 2008)

Received 2 October 2007

Published 29 November 2007



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