A Ruiz et al 2007 Nanotechnology 18 505306 doi:10.1088/0957-4484/18/50/505306
A Ruiz, A Valsesia, F Bretagnol, P Colpo and F Rossi
Show affiliationsNanostructured polydimethylsiloxane stamps have been used to pattern regular nano-arrays of proteins on polyethylene glycol surfaces by microcontact printing. The master was fabricated by using colloidal lithography. In this technique polystyrene nanobeads were used as nanomasks during subsequent oxygen etching and silica deposition. The elastomeric stamps, fabricated by classical replica moulding, reproduced accurately the nanosized features of the moulds. Printing of the proteins was performed by controlling the pressure, enabling the creation of an ordered arrangement of fouling domains (protein) on a non-fouling background (polyethylene glycol). 300 nm diameter poly-L-lysine spots spaced 100 nm were patterned. Such nanofabricated biofunctional surfaces offer promising capabilities for the development of highly compacted, ultra-sensitive biosensing devices.
87.85.Qr Nanotechnologies-design
81.16.Rf Nanoscale pattern formation
Issue 50 (19 December 2007)
Received 20 August 2007, in final form 5 October 2007
Published 23 November 2007
A Ruiz et al 2007 Nanotechnology 18 505306
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