Quick search Find article
Quick search
Find article

Beneficial characteristics of mechanically functional amyloid fibrils evolutionarily preserved in natural adhesives

Anika S Mostaert and Suzanne P Jarvis

Show affiliations


While biological systems are notorious for their complexity, nature sometimes displays mechanisms that are elegant in their simplicity. We have recently identified such a mechanism at work to enhance the mechanical properties of certain natural adhesives. The mechanism is simple because it utilizes a non-specific protein folding and subsequent aggregation process, now thought to be generic for any polypeptide under appropriate conditions. This non-specific folding forms proteinaceous crossed β-sheet amyloid fibrils, which are usually associated with neurodegenerative diseases. Here we show evidence for the beneficial mechanical characteristics of these fibrils discovered in natural adhesives. We suggest that amyloid protein quaternary structures should be considered as a possible generic mechanism for mechanical strength in a range of natural adhesives and other natural materials due to their many beneficial mechanical features and apparent ease of self-assembly.


PACS

87.85.J- Biomaterials

87.15.La Mechanical properties

87.85.Qr Nanotechnologies-design

87.15.N- Properties of solutions of macromolecules

81.16.Dn Self-assembly

87.14.E- Proteins

Subjects

Biological physics

Nanoscale science and low-D systems

Dates

Issue 4 (31 January 2007)

Received 14 August 2006, in final form 5 November 2006

Published 12 December 2006



  1. Beneficial characteristics of mechanically functional amyloid fibrils evolutionarily preserved in natural adhesives

    Anika S Mostaert and Suzanne P Jarvis 2007 Nanotechnology 18 044010

  2. Exact solutions for Wick-type stochastic coupled Kadomtsev–Petviashvili equations

    Bin Chen and Yingchao Xie 2005 J. Phys. A: Math. Gen. 38 815

  3. Generalized Mittag–Leffler functions in the theory of finite-size scaling for systems with strong anisotropy and/or long-range interaction

    H Chamati and N S Tonchev 2006 J. Phys. A: Math. Gen. 39 469

  4. Spherical harmonic decomposition on a cubic grid

    Charles W Misner 2004 Class. Quantum Grav. 21 S243

  5. Rutherford - Scientist Supreme

    H Rechenberg 2000 Eur. J. Phys. 22 191

  6. Resonant and rolling droplet

    S Dorbolo et al 2008 New J. Phys. 10 113021

  7. Rheophysics of cohesive granular materials

    P. G. Rognon et al 2006 Europhys. Lett. 74 644

  8. Perturbative derivations of Larmor's theorem; comparison with other perturbations

    L Dettwiller 1993 Eur. J. Phys. 14 160

  9. Some applications of X-ray analysis methods to steelworks' problems

    A H Jay 1941 J. Sci. Instrum. 18 81

  10. A two-regime approach to the dielectrophoretic effect

    L Benguigiu and I J Lin 1984 J. Phys. D: Appl. Phys. 17 L9

View by subject




Export








Please login to access our web services, or create an account if you don't yet have one.

You must have cookies enabled in your web browser to be able to login.

Username
Password

Forgotten your password? Get a new one here.